Growth Factors & Peptides
Advanced ingredient benefits
Overview of Growth Factors & Peptides
Growth factors are secreted proteins that exert multiple effects on cell growth, metabolism and differentiation. Although the term growth factor was used initially to describe secreted substances that enhanced cell division, this phrase now includes peptides that stimulate or inhibit the progression of cells through mitosis, as well as proteins that act principally to regulate cellular differentiation.
To accomplish these and other biological actions, growth factors activate specific cellular receptors. Receptors are modular proteins that can bind to cells and transmit the information to induce changes in cellular biochemistry. There is an explosive increase in knowledge about growth factor and peptides in biology. This has included the characterisation of many growth factors in the human body, their receptors and binding proteins.
Through novel molecular biological techniques it is possible to produce pure recombinant growth factors and peptides. Growth factors and peptides have excellent proven safety and effectiveness. Many hormones also regulate the growth and development of cells and tissue. But growth factors are not hormones, even if they can show certain similarities.
Unlike hormones growth factors are not produced in specialised organs or glands but by many tissues in the body. Hormones act at locations distant from their sites (systemic action) of synthesis and have an endocrine mode of action. Growth factors act at the location where they are synthetised or administrated (paracrine, autocrine and juxtacrine modes). This mechanism of action of peptides and growth factors guarantee a high safety profile as they act only locally on adjacent cells.
Peptides in Skincare & Chemical Peels
Peptides induce revitalisation of the cutaneous metabolism and ensure long-term rejuvenation of the cells vital functions. They are obtained by a specific reproducible extraction process allowing the selection of a high fraction of peptides whose molecular weight ranges from 1000 to 6000 Daltons. These peptidic or heteropeptidic fractions are characterised by their ability to boost vital cellular functions, due to a growth factor like activity.
Peeling solutions have the ability to penetrate deeper into the epidermis compared to traditional serums and creams. You will note that the ekseption range of organic chemical peels contain peptides. Adding peptides into the peels, results in the peptides being able to reach deeper layers of the skin, when compared to cosmetic topical application.